Temporal trajectories of important diseases in the life course and premature mortality in the UK Biobank

Xianwen Shang, Xueli Zhang, Yu Huang, Zhuoting Zhu, Xiayin Zhang, Shunming Liu, Jiahao Liu, Shulin Tang, Wei Wang, Honghua Yu, Zongyuan Ge, Mingguang He
May 2022
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Abstract

Little is known regarding life-course trajectories of important diseases. We aimed to identify diseases that were strongly associated with mortality and test temporal trajectories of these diseases before mortality.

Type
Journal article
Publication
BMC Medicine
cancer cardiovascular disease chronic kidney disease disease trajectory hypertension multimorbidity multiple chronic diseases premature mortality
Xueli Zhang
Xueli Zhang
PhD of Bioinformatics, Assistant Professor

My research interest is to explore the comorbidity relationship of diseases based on complex networks and to find new combination markers, and has constructed multiple biomarker databases and prediction models.

Shunming Liu
Shunming Liu
MSc in Technical Economy and Management

I’m drawn to the study of wearable devices and possess expertise in machine learning and big data analysis. My goal is to seamlessly blend technology and medicine to develop enhanced and precise medical solutions.